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Best Luxury Midsize Cars for 2021

The best luxury midsize cars combine the smooth-riding opulence of large luxury cars with the agility of small luxury cars. All Rankings »

11 cars

2021 BMW 5-Series

Exhilarating power, a serene ride, a top-notch safety score, and a cavernous cabin are just some of the traits that propel the 2021 BMW … read more »

8.5SCORE

$54,200 - $103,500 MSRP

25 City / 33 Hwy MPG

8.5SCORE

$54,200 - $103,500 MSRP

25 City / 33 Hwy MPG

2021 Genesis G80

The 2021 Genesis G80 ranks near the top of the luxury midsize car class thanks to its quiet and comfortable interior, top-notch materials, u read more »

8.5SCORE

$47,700 - $62,250 MSRP

- TBD - City / - TBD - Hwy MPG

8.5SCORE

$47,700 - $62,250 MSRP

- TBD - City / - TBD - Hwy MPG

2021 Audi A6

The 2021 Audi A6 ranks near the top of the luxury midsize car class thanks to its opulent interior, refined ride, and powerful engines. read more »

8.2SCORE

$54,900 - $74,400 MSRP

24 City / 32 Hwy MPG

8.2SCORE

$54,900 - $74,400 MSRP

24 City / 32 Hwy MPG

2021 Lexus ES

The 2021 Lexus ES ranks near the top of the luxury midsize car class thanks to its composed ride and handling, comfortable and spacious … read more »

8.2SCORE

$39,900 - $48,900 MSRP

22 City / 33 Hwy MPG

8.2SCORE

$39,900 - $48,900 MSRP

22 City / 33 Hwy MPG

2020 Lexus GS

The 2020 Lexus GS provides both a comfortable ride and agile handling. It also touts lots of standard safety technology, and it has ample … read more »

8.1SCORE

$51,065 - $85,010 MSRP

20 City / 28 Hwy MPG

8.1SCORE

$51,065 - $85,010 MSRP

20 City / 28 Hwy MPG

2020 Mercedes-Benz E-Class

The 2020 Mercedes-Benz E-Class has a premium interior, cutting-edge technology, a cushioned ride, and a range of brawny engine options, but read more »

8.1SCORE

$54,050 - $111,750 MSRP

20 City / 28 Hwy MPG

8.1SCORE

$54,050 - $111,750 MSRP

20 City / 28 Hwy MPG

2021 Acura TLX

The redesigned 2021 Acura TLX ranks in the bottom half of the luxury midsize car class. It has a quality interior, a poised ride, … read more »

8.0SCORE

$37,500 - $48,300 MSRP

22 City / 31 Hwy MPG

8.0SCORE

$37,500 - $48,300 MSRP

22 City / 31 Hwy MPG

2021 Volvo S90

The 2021 Volvo S90 offers two good engine choices, an elegant interior, and a spacious back seat, but it’s relegated to the bottom half … read more »

7.8SCORE

$51,550 - $60,050 MSRP

21 City / 31 Hwy MPG

7.8SCORE

$51,550 - $60,050 MSRP

21 City / 31 Hwy MPG

2020 Lincoln MKZ

The 2020 Lincoln MKZ sits near the bottom of the luxury midsize car class. It has a comfortable ride and a large trunk, but … read more »

7.2SCORE

$36,750 - $44,500 MSRP

20 City / 31 Hwy MPG

7.2SCORE

$36,750 - $44,500 MSRP

20 City / 31 Hwy MPG

2021 Cadillac CT5

The 2021 Cadillac CT5 comes up short in terms of interior quality, trunk space, and driving engagement compared to many of its rivals. This read more »

Not Yet Ranked

N/A MSRP

23 City / 32 Hwy MPG

Not Yet Ranked

N/A MSRP

23 City / 32 Hwy MPG

2020 Jaguar XF

The 2020 Jaguar XF delivers engaging performance and sports a comfortable interior, but many rivals look and feel more luxurious. The 2020 X read more »

Not Yet Ranked

$51,100 - $71,800 MSRP

25 City / 34 Hwy MPG

Not Yet Ranked

$51,100 - $71,800 MSRP

25 City / 34 Hwy MPG

More on Luxury Midsize Cars

Top-ranked midsize luxury cars offer a compelling mix of comfort, features, and performance. These models deliver smooth rides, composed handling, and powerful engine options. They also offer upscale interiors with spacious rear seats, attractive designs, and high-end materials. Class-leading luxury midsize cars are available with the latest high-tech features, such as large infotainment screens and automated collision prevention systems.

Fuel economy continues to improve as more hybrid, diesel, and turbocharged models enter the market, yet horsepower continues to climb as well. It's not unusual to see models with over 500 horsepower in this class.

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